Dimethylamine → HCID 68441266, compound

Participants

Reaction Steps

Similar to example 6a, 50.0 mg of (2S,4R,5R)-4-(4-methoxy-phenyl)-5-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-piperidin-1,2-dicarboxylic acid 1-benzyl ester (from example 3b) are allowed to react with dimethylamine to afford the title compound as a yellow oil. Rf=0.04 (dichlormethane-methanol 98:2); Rt=4.85.

Provenance & Evidence