Methanamine, N-methoxy-, hydrochloride (1:1) → HCID 86621628, compound

Participants

Reaction Steps

According to general procedure D, 1.65 g of 3-[(2S,4R,5R)-4-(4-methoxy-phenyl)-5-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulfonyl)-piperidin-2-yl]-propionic acid and 271 mg of N,O-dimethylhydroxylamine hydrochloride are used to afford the title compound as a beige oil. Rf=0.18 (EtOAc-heptane 2:1); Rt=5.09.

Provenance & Evidence