HuagongsheHuagongshe Chemistry Print Report · For research reference only
Borane;tetrahydrofuran → HCID 68442993, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Borane;tetrahydrofuran | HCID 2723981 | — |
| Reactant | HCID 68442728 | HCID 68442728 | — |
| Product | HCID 68442993 | HCID 68442993 | — |
Reaction Steps
Similar to procedure 29a, 800 mg of 4-[(2S,4R,5R)-4-(4-methoxy-phenyl)-5-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulfonyl)-piperidin-2-yl]-butan-2-one and 3.0 ml of borane-tetrahydrofuran complex (1N in tetrahydrofuran) are used to afford the title compound as a yellow oil. Rf=0.22 (EtOAc-heptane 2:1); Rt=5.00.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687495B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-87f1d8341f604243bba18f16384ad6e8 |
| Source note | uspto-grants-2010_03 |