HCID 68442591, compound → HCID 68440908, compound

HRID 2246985Notes

Reaction equation

HRID 2246985 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C@H:9]2[CH2:14][C@@H:13]([CH:15]=[C:16]3[CH2:21][CH2:20][O:19][CH2:18][CH2:17]3)[NH:12][CH2:11][C@@H:10]2[O:22][CH:23]([C:34]2[CH:35]=[CH:36][C:37]3[O:42][CH2:41][CH2:40][N:39]([CH2:43][CH2:44][CH2:45][O:46][CH3:47])[C:38]=3[CH:48]=2)[S:24]([C:27]2[CH:32]=[CH:31][C:30]([CH3:33])=[CH:29][CH:28]=2)(=[O:26])=[O:25])=[CH:5][CH:4]=1>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C@H:9]2[CH2:14][C@@H:13]([CH2:15][CH:16]3[CH2:21][CH2:20][O:19][CH2:18][CH2:17]3)[NH:12][CH2:11][C@@H:10]2[O:22][CH:23]([C:34]2[CH:35]=[CH:36][C:37]3[O:42][CH2:41][CH2:40][N:39]([CH2:43][CH2:44][CH2:45][O:46][CH3:47])[C:38]=3[CH:48]=2)[S:24]([C:27]2[CH:32]=[CH:31][C:30]([CH3:33])=[CH:29][CH:28]=2)(=[O:26])=[O:25])=[CH:7][CH:8]=1

Participants

3

Reactant 1

HCID 68442591HCID 68442591, compound

Product 1

HCID 68440908HCID 68440908, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

According to general procedure E (using ethanol as solvent), 6-[(3R,4R,6S)-4-(4-methoxy-phenyl)-6-(tetrahydro-pyran-4-ylidenemethyl)-1-(toluene-4-sulfonyl)-piperidin-3-yloxymethyl]-4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazine is used to afford the title compound, which is identified based on its Rf value.

Sources & evidence

ORD record
ord-b881c740632c4a069066409716787efa
Source dataset
uspto-grants-2010_03
Patent number
US07687495B2

Reaction notes

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