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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2247002Generated: October 30, 2026

Tetrahydrofuran → HCID 24885422, compound

https://huagongshe.com/reaction/2247002

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantDiethyl (cyanomethyl)phosphonateHCID 75676—
ReactantLithium BromideHCID 82050—
ReactantHCID 68694918HCID 68694918—
ProductHCID 24885422HCID 24885422—

Reaction Steps

The mixture of triethylamine (13.8 mmol), lithium bromide (8.2 mmol) and diethylcyanomethylphosphonate (7.2 mmol) in 25 ml tetrahydrofuran was stirred for 20 minutes at room temperature. To the suspension, (S)-{3-[4-(4-oxo-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (6.9 mmol) was added. The reaction mixture stirred for 5 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07687627B2
Source datasetuspto-grants-2010_03
ORD IDord-306920643ca047859e22df0af2329142
Source noteuspto-grants-2010_03