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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2247007Generated: November 1, 2026

Water → HCID 11394934, compound

https://huagongshe.com/reaction/2247007

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTriphenylphosphineHCID 11776—
ReactantHCID 11750153HCID 11750153—
SolventTetrahydrofuranHCID 8028—
ProductHCID 11394934HCID 1139493467%

Reaction Steps

The title compound was prepared by reacting (S)-N-{3-[4-(4-fluoro-4-azidomethylpiperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (0.73 mmol) with triphenylphosphine (1.27 mmol) in tetrahydrofuran (10 ml) at a temperature 25° C. for six hours and then refluxing for overnight after addition of drop of water followed by purification using silica gel column chromatography in 67% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07687627B2
Source datasetuspto-grants-2010_03
ORD IDord-2786c827f1284eb3ab1c9ba475406bf4
Source noteuspto-grants-2010_03