Triethylamine → HCID 11374585, compound

Participants

Reaction Steps

The title compound was prepared by reacting (S)-N-{3-[4-(4-fluoro-4-aminomethylpiperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (1.30 mmol) with methane sulfonyl chloride (1.40 mmol) and triethylamine (2.08 mmol) in dichloromethane (10 ml) at a temperature 25° C. for 2 hours followed by purifification of the compound using silica gel column chromatography in 75% yield.

Provenance & Evidence