HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → HCID 11465078, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | HCID 11382912 | HCID 11382912 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 11465078 | HCID 11465078 | 80% |
Reaction Steps
The title compound was prepared by reacting (S)-N-{3-[4-(1-oxa-6-aza-spiro[2.5]oct-6-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (1.37 mmol) with piperazine (2.06 mmol) in methanol (10 ml) at a temperature 25° C. for 14 hours and by purifying the compound by silica gel column chromatography in 80% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687627B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-39ab7234cf6c47aeb3efe1cade0df04e |
| Source note | uspto-grants-2010_03 |