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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2247040Generated: November 1, 2026

4-Nitroaniline → HCID 11283345, compound

https://huagongshe.com/reaction/2247040

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-NitroanilineHCID 7475—
ReactantSodium CyanideHCID 8929—
ReactantN-[(5S)-3-[3-fluoro-4-(4-oxopiperidinyl)phenyl]-2-oxo-5-oxazolidinyl]methylacetamideHCID 54375226—
ProductHCID 11283345HCID 1128334561%

Reaction Steps

By using procedure as described in Example 45 and by reacting (S)-N-{3-[4-(4-oxo-piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide with sodium cyanide and 4-nitroaniline the compound was obtained in 61% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07687627B2
Source datasetuspto-grants-2010_03
ORD IDord-91beacd3988f40bdbe3823ec7e535901
Source noteuspto-grants-2010_03