Acetyl chloride → HCID 60133570, compound

Participants

Reaction Steps

The title compound was prepared by reacting (S)-N-{3-[4-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-amine (0.2 mmol, Example I) with acetyl chloride (2.1 mmol), n-butyl lithium (0.2 mmol) in tetrahydrofuran at a temperature 0-25° C. for 3 hours followed by silica gel column chromatographic purification in % yield.

Provenance & Evidence