Diethyl {[di(prop-2-en-1-yl)amino]methyl}phosphonate → Diethyl [(1H-pyrrol-1-yl)methyl]phosphonate

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Reaction Conditions

Reaction Steps

0.1 g (0.41 mmole) of the diethyl diallylaminomethylphosphonate prepared in example 25 was dissolved in 2 ml chlorobenzene, then 0.014 g (0.02 mmole) of the bimetallic ruthenium complex 3.e prepared in example 24 was added and the mixture was stirred for 16 hours at 60° C. The catalyst was removed after evaporation of the chlorobenzene by column chromatography, yielding 0.04 g (0.18 mmole, yield 45%) diethyl 1H-pyrrole-1-ylmethylphosphonate. This product was further characterised by the following spectra:

Provenance & Evidence