HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22249265, compound → HCID 22249256, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22249265 | HCID 22249265 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 22249256 | HCID 22249256 | — |
Reaction Steps
A mixture of N-[4-(isopropyl)phenyl]{2-methylthio-4-[(4-pyridylmethyl)amino]pyrimidin-5-yl}carboxamide (50 mg, 0.13 mmol, Step B) and Raney-Ni in EtOH (10 mL) was heated at reflux for 2 h. The resulting mixture was filtered, and the filtrate was concentrated to give the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687643B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-525d8437ff99478d9babd1bbec48aea0 |
| Source note | uspto-grants-2010_03 |