3-Fluoro-4-(trifluoromethyl)benzaldehyde → N-[5-(4-Methanesulfonyl-3-trifluoromethyl-phenyl)-4-methyl-thiazol-2-yl]-acetamide

Participants

Role	Name	HCID	Charge
Reactant	3-Fluoro-4-(trifluoromethyl)benzaldehyde	HCID 2737537	—
Reactant	N-[5-(3-fluoro-4-methylsulfonylphenyl)-4-methyl-1,3-thiazol-2-yl]acetamide	HCID 57351276	—
Product	N-[5-(4-Methanesulfonyl-3-trifluoromethyl-phenyl)-4-methyl-thiazol-2-yl]-acetamide	HCID 70684690	—

Reaction Steps

The title compound is prepared by an analogous procedure to N-[5-(3-fluoro-4-methane-sulfonyl-phenyl)-4-methyl-thiazol-2-yl]-acetamide (Example 64) by replacing 3,4-difluoro-benzaldehyde with 3-fluoro-4-trifluoromethylbenzaldehyde.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07687637B2
Source dataset	uspto-grants-2010_03
ORD ID	ord-c983d7c9f8944bbdb0268676f9e389ff
Source note	uspto-grants-2010_03