Ammonia → [5-(3-Fluoro-4-methanesulfonyl-phenyl)-4-methyl-thiazol-2-yl]-urea

Participants

Role	Name	HCID	Charge
Reactant	Ammonia	HCID 222	—
Reactant	1-[5-(3-Fluoro-4-methanesulfonyl-phenyl)-4-methyl-thiazol-2-yl]-3-(2-hydroxy-ethyl)-urea	HCID 86598421	—
Product	[5-(3-Fluoro-4-methanesulfonyl-phenyl)-4-methyl-thiazol-2-yl]-urea	HCID 57872135	—

Reaction Steps

The title compound is prepared by the same procedure as 1-[5-(3-fluoro-4-methanesulfonyl-phenyl)-4-methyl-thiazol-2-yl]-3-(2-hydroxy-ethyl)-urea (Example 88) by replacing 2-aminoethanol (part 88b) in this example with ammonia.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07687637B2
Source dataset	uspto-grants-2010_03
ORD ID	ord-15611d35f3ad4cdebf18d220727a4227
Source note	uspto-grants-2010_03