HCID 86602489, Verbindung → 1-(2-Methylphenyl)ethan-1-amine

HRID 2247581Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2247581
[N:1]([CH:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[CH3:12])[CH3:5])=[N+]=[N-].[H][H]>CO.[C].[Pd]>[C:7]1([CH3:12])[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[CH:4]([NH2:1])[CH3:5]

Komponenten

5

Edukt 2

HCID 86602489HCID 86602489, VerbindungHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 33910421-(2-Methylphenyl)ethan-1-amineAusbeute 77,2 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

10% palladium-carbon (water content: 50%, 50 mg) was added to a solution of 1-(1-azidoethyl)-2-methylbenzene (744 mg) in methanol (5 mL), and the reaction solution was stirred in a hydrogen atmosphere at room temperature for 1 hour. The reaction solution was filtered on a celite, and the filtrate was concentrated under reduced pressure to obtain 482 mg of the title compound. The physical properties of the compound are as follows.

Aufarbeitung

  1. filtrationThe reaction solution was filtered on a celite
  2. concentrationthe filtrate was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-51b236154e06417c8ac2698bc764af2c
Quelldatensatz
uspto-grants-2010_03
Patentnummer
US07687640B2

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