反应详情

From 9.46 g. 1,4-Dimethyl-7-hydroxy-2-oxo-1,2-dihydroquinoline and 15.8 g. 3-[4-(4-chlorobenzyl)-piperazin-1-yl]-propyl chloride, in the manner described in Example 1, there are obtained 15.2 g. (63.8% of theory) 1,4-dimethyl-7-{3-[4-(4-chlorobenzyl)-piperazin-1-yl]-propoxy}-2-oxo-1,2-dihydroquinoline monohydrochloride. Thermoanalysis shows a melting point of 189° C. The corresponding dihydrochloride melts at 260°-263° C.

1. customare obtained 15.2 g