反应详情

The title compound (0.14 g) was synthesized in a yield of 92% as a white crystalline solid by conducting the reaction similar to that mentioned in Example 3 (3e) using methyl 1-[(5-{5-[3-chloro-4-(3-fluorophenoxy)phenyl]-1,2,4-oxadiazol-3-yl}-4-ethyl-2-thienyl)methyl]azetidine-3-carboxylate (0.16 g, 0.30 mmol) that was obtained in Example 16 (16c), a 1 N aqueous solution of sodium hydroxide (0.89 mL, 0.89 mmol), and acetic acid (51 μL, 0.89 mmol).

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