Acetic Acid → HCID 11978162, compound

Participants

Reaction Steps

The title compound (140 mg) was synthesized in a yield of 67% as a white crystalline solid by conducting the reaction similar to that mentioned in Example 1 (1g) using methyl 1-[(5-{5-[4-(2-chlorophenoxy)phenyl]-1,2,4-oxadiazol-3-yl}-4-ethyl-2-thienyl)methyl]azetidine-3-carboxylate (0.21 g, 0.41 mmol) that was obtained in Example 19 (19c), lithium hydroxide monohydrate (38 mg, 0.90 mmol), acetic acid (49 μL, 0.90 mmol), and oxalic acid (18 mg, 0.20 mmol).

Provenance & Evidence