HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 11978047, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 68523928 | HCID 68523928 | — |
| Product | HCID 11978047 | HCID 11978047 | 83% |
Reaction Steps
The title compound (0.11 g) was synthesized in a yield of 83% as a white crystalline solid by conducting the reaction similar to that mentioned in Example 3 (3e) using methyl 1-[(4-ethyl-5-{5-[3-fluoro-4-(3-fluorophenoxy)phenyl]-1,2,4-oxadiazol-3-yl}-2-thienyl)methyl]azetidine-3-carboxylate (0.14 g, 0.27 mmol) that was obtained in Example 20 (20c) and a 1 N aqueous solution of sodium hydroxide (0.81 mL, 0.81 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687491B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-973af6e8fbec4819a37a6e615bebd57f |
| Source note | uspto-grants-2010_03 |