反应详情

6.8 g (0.1 mol) of 50% strength hydrogen peroxide were added to a mixture of 18.4 g (0.1 mol) of 2-methylthiomethyl-4-hydroxy-5,6-dimethylpyrimidine in 100 ml of glacial acetic acid at 10° C. The mixture was subsequently stirred for 3 hours, without cooling, about 300 ml of ether were added and the product which had precipitated was filtered off. 17 g (85% of theory) of 2-methysulphinylmethyl-4-hydroxy-5,6-dimethylpyrimidine were thus obtained in the form of a grey powder with a melting point of 112° C. ##STR7##

1. temperaturewithout cooling
2. customthe product which had precipitated
3. filtrationwas filtered off