反应详情

The title compound (0.13 g) was synthesized in a yield of 83% as a white crystalline solid by conducting the reaction similar to that mentioned in Example 21 (21d) using methyl 1-({5-[5-(4-isobutyl-3-methylphenyl)-1,2,4-oxadiazol-3-yl]pyridin-2-yl}methyl)azetidine-3-carboxylate (0.14 g, 0.34 mmol) that was obtained in Example 28 (28b), a 1 N aqueous solution of sodium hydroxide (11.0 mL, 1.0 mmol), acetic acid (58 μL, 1.0 mmol), and oxalic acid (15 mg, 0.17 mmol).

1. customthe reaction similar to