2,4,5-Trichlorobenzenesulfonyl chloride → HCID 19362491, compound

HRID 2247790Notes

Reaction equation

HRID 2247790 reaction equation
[C:1]([C:3]([C:12]#[N:13])=[CH:4][C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][CH:6]=1)#[N:2].[Cl:14][C:15]1[CH:20]=[C:19]([Cl:21])[C:18]([Cl:22])=[CH:17][C:16]=1[S:23](Cl)(=[O:25])=[O:24]>N1C=CC=CC=1>[Cl:14][C:15]1[CH:20]=[C:19]([Cl:21])[C:18]([Cl:22])=[CH:17][C:16]=1[S:23]([O:11][C:8]1[CH:9]=[CH:10][C:5]([CH:4]=[C:3]([C:12]#[N:13])[C:1]#[N:2])=[CH:6][CH:7]=1)(=[O:25])=[O:24]

Participants

4

Reactant 2

HCID 275752,4,5-Trichlorobenzenesulfonyl chlorideHCID 92970Tyrphostin 8

Product 1

HCID 19362491HCID 19362491, compoundYield 87.7%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

1.7 g of 4-(2,2'-dicyanovinyl)phenol and 2.7 g of 2,4,5-trichlorobenzenesulfonyl chloride were dissolved in 10 ml of pyridine and reacted at 80° C. for 30 minutes. Crystals were precipitated by cooling to the room temperature and adding water, filtered and recrystallized from toluene to obtain 3.5 g of 4-(2,2'-dicyanovinyl)phenyl 2,4,5-trichlorobenzenesulfonate as white crystals. Melting point=165-166° C.

Workup

  1. customreacted at 80° C. for 30 minutes
  2. customCrystals were precipitated
  3. additionadding water
  4. filtrationfiltered
  5. customrecrystallized from toluene

Sources & evidence

ORD record
ord-95ebb5cbb95d41c9a5407f165c65841c
Source dataset
uspto-grants-1991_08
Patent number
US05037714

Reaction notes

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