HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10899886, compound → 3-(3-Methoxy-3-methylbutyl)-5-methylcyclohexanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10899886 | HCID 10899886 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 3-(3-Methoxy-3-methylbutyl)-5-methylcyclohexanol | HCID 14793995 | 75.8% |
Reaction Steps
A mixture of 3-(3-methoxy-3-methylbut-1-yl)-5-methylcyclohex-5-en-1-one (1.0 g, 0.0048 mol) in 2-propanol (40 mL) and Raney nickel (about 0.1 g) was shaken under hydrogen (37 psi) at 25~C. for 16 hours. Subsequent workup yielded 3-(3-methoxy-3-methylbut-1-yl)-5-methylcyclohexan-1-ol (0.78 g) as a mixture of four diastereoisomers (ratio 8.1:20.6:57.8:7.8).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05037802 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-43388908c4dd4309982744d19d995f11 |
| Source note | uspto-grants-1991_08 |