Trifluoroacetic acid → 8-Amino-2E-octenoic acid trifluoroacetate salt

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Reaction Steps

A mixture of 45 mL trifluoroacetic acid and 5 mL water was chilled in an ice bath while 34 g (0.132 mole) of (9) was added with stirring. The resulting solution was allowed to warm to room temperature over 1.5 h and then evaporated under a slow nitrogen stream overnight. The residue was triturated with ether. The solid was filtered, rinsed well with ether and dried to yield 21 g of the title compound (10), mp 77°-78° C. Anal. Calcd. for C10H15NO4F3 : C, 44.28; H, 5.95; N, 5.16. Found: C, 44.07; H, 5.96; N, 5.09.

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