Sodium Acetate → HCID 10064740, compound

HRID 2247830Notes

Reaction equation

HRID 2247830 reaction equation
N1CCC([N:7]([S:15]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)(=[O:17])=[O:16])[CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=O)CC1.[C:24]([O-])(=O)[CH3:25].[Na+]>C(OC(=O)C)(=O)C>[N:7]1([C:21]2[CH:20]=[CH:19][C:18]([S:15]([N:7]3[CH2:8][CH2:9][CH2:10][CH2:11][C:12]3=[O:14])(=[O:16])=[O:17])=[CH:23][CH:22]=2)[CH2:25][CH2:24][CH2:10][CH2:9][CH2:8]1

Participants

4

Reactant 2

HCID 517045Sodium AcetateHCID 53822007HCID 53822007, compound

Product 1

HCID 10064740HCID 10064740, compoundYield 185.8%

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

5 g of product obtained in Stage B are heated to reflux for 4 hours with 5 g of sodium acetate in 50 cm3 of acetic anhydride. The mixture is cooled to room temperature and evaporated to dryness, the residue is taken up in 50 cm3 of water, filtered off and dried and 4.4 g of expected crude product are obtained. M.p. 140°-145° C. After crystallization in ethanol, 3.4 g of pure product are obtained. M.p. 145°-146° C.

Workup

  1. customevaporated to dryness
  2. filtrationfiltered off
  3. customdried

Sources & evidence

ORD record
ord-ae0cbe0512e848df865d7b6f6a96cca7
Source dataset
uspto-grants-1991_08
Patent number
US05037822

Reaction notes

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