Sodium Acetate → HCID 10065607, compound

HRID 2247833Notes

Reaction equation

HRID 2247833 reaction equation
[N:1]1([C:8]2[CH:13]=[CH:12][C:11]([S:14]([NH:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([OH:24])=O)(=[O:16])=[O:15])=[CH:10][CH:9]=2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C([O-])(=O)C.[Na+]>C(OC(=O)C)(=O)C>[N:1]1([C:8]2[CH:13]=[CH:12][C:11]([S:14]([N:17]3[CH2:18][CH2:19][CH2:20][CH2:21][C:22]3=[O:24])(=[O:16])=[O:15])=[CH:10][CH:9]=2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 517045Sodium AcetateHCID 10066729HCID 10066729, compound

Product 1

HCID 10065607HCID 10065607, compoundYield 92.2%

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

4 g of product obtained in Stage B are heated to reflux for 1 hour with 4 g of sodium acetate in 80 cm3 of acetic anhydride. The mixture is cooled to room temperature and evaporated to dryness, the residue is taken up in 60 cm3 of water, filtered and dried and 3.5 g of expected product are obtained. After crystallization in isopropanol, 2.3 g of product are obtained. M.p. 164°- 165° C.

Workup

  1. customevaporated to dryness
  2. filtrationfiltered
  3. customdried

Sources & evidence

ORD record
ord-705b30b447b744d598466b569f042f0a
Source dataset
uspto-grants-1991_08
Patent number
US05037822

Reaction notes

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