HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylthiouracil → 6-methyl-2-[(pyridin-2-yl)methyl]thio-4(3H)-pyrimidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylthiouracil | HCID 667493 | — |
| Reactant | 2-(Chloromethyl)pyridin-1-ium chloride | HCID 11344184 | — |
| Product | 6-methyl-2-[(pyridin-2-yl)methyl]thio-4(3H)-pyrimidinone | HCID 135559186 | 45% |
Reaction Steps
The title compound is prepared from 6-methyl-2-thiouracil and 2-chloromethylpyridinium chloride by using the process described in Example 12. After recrystallization from 2-propanol the title compound is obtained as a yellowish crystalline substance in a yield of 45%, m.p.: 154°-156° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05037830 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-28250a125de84638a063a1da87e71c1c |
| Source note | uspto-grants-1991_08 |