3-Carboxy-2,3-dihydroxypropanoate → HCID 14723139, compound

HRID 2247885Notes

Reaction equation

HRID 2247885 reaction equation
CS[CH2:3][C:4]1[NH:18][C:17]2[C:19]3[C:5]=1[CH2:6][C@@H:7]1[C:12]([C:13]=3[CH:14]=[CH:15][CH:16]=2)=[CH:11][C@H:10]([NH:20][C:21](=[O:27])[N:22]([CH2:25][CH3:26])[CH2:23][CH3:24])[CH2:9][N:8]1[CH2:28][CH2:29][CH3:30].[C:31](C(C(C([O-])=O)O)O)(O)=O>N1C=CC=CC=1>[CH2:25]([N:22]([CH2:23][CH3:24])[C:21]([NH:20][C@H:10]1[CH2:11][C@H:12]2[C@@H:7]([CH2:6][C:5]3[C:19]4[C:17](=[CH:16][CH:15]=[CH:14][C:13]2=4)[NH:18][C:4]=3[CH2:3][CH3:31])[N:8]([CH2:28][CH2:29][CH3:30])[CH2:9]1)=[O:27])[CH3:26]

Participants

4

Reactant 2

HCID 36671293-Carboxy-2,3-dihydroxypropanoateHCID 15067687HCID 15067687, compound

Product 1

HCID 14723139HCID 14723139, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

3-(9,10-didehydro-2-methylthiomethyl-6-n-propyl-8α-ergolinyl)-1,1-diethylurea, yield 50% as hydrogen tartrate, [α]D +169° (c=0.5 in pyridine).

Sources & evidence

ORD record
ord-9a7d1b97d2e44e7e99175086f387e88e
Source dataset
uspto-grants-1991_08
Patent number
US05037832

Reaction notes

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