HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → HCID 57125042, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | 4-Chloroaniline | HCID 7812 | — |
| Reactant | Ethyl 6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-3-carboxylate | HCID 208414 | — |
| Reactant | Ethyl 7-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidine-3-carboxylate | HCID 15570105 | — |
| Product | HCID 57125042 | HCID 57125042 | 60.2% |
Reaction Steps
The process according to Example 6 is carried out except that p-chloro-aniline is replaced by aniline and ethyl-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyrimidine-3-carboxylate is replaced by ethyl-7-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyrimidine-3-carboxylate, respectively. Thus ethyl-9-(phenyl-hydrazono)-7-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyrimidine-3-carboxylate is obtained with a yield of 60.2%. Mp.: 165°-167° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04234586 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-3dc8f4a979004b9a81330c59d4f82c21 |
| Source note | uspto-grants-1980_11 |