Pyridine → 3-Hydroxy-5-methoxyphenyl valerate

Participants

Reaction Steps

One equivalent of 3,5-dihydroxyanisole was reacted with one equivalent of valeroyl chloride in pyridine as solvent for a period of one hour by the reaction scheme shown in FIG. 2. The solvent pyridine was removed from the reaction mixture to give 3-hydroxy-5-methoxyphenyl valerate (the monoester) and 5-methoxyphenyl-1,3-divalerate (the diester) in approximately equal amounts.

Provenance & Evidence