Methyl iodide → HCID 178504015, compound

HRID 224804Notes

Reaction equation

HRID 224804 reaction equation
[CH3:1][CH:2]([CH3:15])[CH2:3][CH2:4][N:5]1[C:9]([NH:10][C:11]([NH2:13])=[S:12])=[CH:8][C:7]([CH3:14])=[N:6]1.[CH3:16][I:17]>C(O)C>[IH:17].[CH3:1][CH:2]([CH3:15])[CH2:3][CH2:4][N:5]1[C:9]([NH:10][C:11](=[NH:13])[S:12][CH3:16])=[CH:8][C:7]([CH3:14])=[N:6]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 12763849HCID 12763849, compound

Product 1

HCID 178504015HCID 178504015, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

[1-(3-methylbutyl)-3-methyl-5-pyrazolyl] thiourea (23.0 g) was dissolved in 250 ml. ethanol and 15.62 g. methyl iodide and refluxed for 4 hours. The ethanol was concentrated in vacuum and ether added to get 29.3 g. product, mp 128°-131° C.

Workup

  1. concentrationThe ethanol was concentrated in vacuum and ether
  2. additionadded
  3. customto get 29.3 g

Sources & evidence

ORD record
ord-3e57a956ddec4cb7bc4c41f90b6bbab1
Source dataset
uspto-grants-1980_11
Patent number
US04234594

Reaction notes

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