HCID 23260664, compound → HCID 19883910, compound

HRID 2248085Notes

Reaction equation

HRID 2248085 reaction equation
[OH:1][CH:2]([C:4]1([OH:27])[CH2:21][CH2:20][CH:19]2[CH:6]([C:7](=[O:26])[C:8]3[C:17]([CH2:18]2)=[C:16]([O:22][CH3:23])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]=3[O:24][CH3:25])[CH2:5]1)[CH3:3]>C1C=CC=CC=1.C(=O)([O-])[O-].[Ag+2]>[C:2]([C:4]1([OH:27])[CH2:21][CH2:20][CH:19]2[CH:6]([C:7](=[O:26])[C:8]3[C:17]([CH2:18]2)=[C:16]([O:22][CH3:23])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]=3[O:24][CH3:25])[CH2:5]1)(=[O:1])[CH3:3]

Participants

4

Reactant 1

HCID 23260664HCID 23260664, compound

Product 1

HCID 19883910HCID 19883910, compoundYield 100.5%

Reagents, catalysts & solvents 2

HCID 178418647HCID 178418647, compoundCatalystHCID 241BenzeneSolvent

Procedure

0.1 g of 1,2,3,4,4a,5,12,12a-octahydro-2-(1-hydroxyethyl)-2-hydroxy-6,11-dimethoxy-12-oxo-naphthacene, prepared as described in Example 12, in benzene was treated with 1 g of silver carbonate at refluxing temperature. After filtering off the inorganic solids and removing the solvent, 0.1 g of the title product was obtained.

Workup

  1. temperatureat refluxing temperature
  2. filtrationAfter filtering off the inorganic solids
  3. customremoving the solvent

Sources & evidence

ORD record
ord-c641fb2feac144dda07806a40f56af50
Source dataset
uspto-grants-1991_08
Patent number
US05037970

Reaction notes

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