Ammonia → HCID 14700379, compound

HRID 2248092Notes

Reaction equation

HRID 2248092 reaction equation
Cl[C:2]1[C:11]2[N:12]=[CH:13][N:14]([CH:15]=[C:16]([CH3:18])[CH3:17])[C:10]=2[C:9]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[N:3]=1.[NH3:19]>CO>[CH3:17][C:16]([CH3:18])=[CH:15][N:14]1[C:10]2[C:9]3[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=3[N:3]=[C:2]([NH2:19])[C:11]=2[N:12]=[CH:13]1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 14700375HCID 14700375, compound

Product 1

HCID 14700379HCID 14700379, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Similarly, the isomer 4-chloro-1-(2-methyl-1-propenyl)-1H-imidazo[4,5-c]quinoline was reacted with 19% ammonia in methanol to provide 1-(2-methyl-1-propenyl)-1H-imidazo[4,5-c]quinolin-4-amine, m.p. 284°-289° C. after recrystallization from ethanol. Analysis: Calculated for C14H14N4 : %C, 70.6; %H, 5.9; %N, 23.5; Found: %C, 70.6; %H, 5.9; %N, 23.4.

Sources & evidence

ORD record
ord-99b6c39b80cd4718b2f5f372b2dd9cc6
Source dataset
uspto-grants-1991_08
Patent number
US05037986

Reaction notes

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