Chlorobenzene sulfochloride → HCID 178521404, compound

HRID 2248128Notes

Reaction equation

[NH:1]1[C:5]([NH:6][C:7](=[O:19])[CH2:8][O:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([CH2:16][CH2:17][NH2:18])[CH:11]=2)=[N:4][N:3]=[N:2]1.[S:20](Cl)([OH:23])(=O)=[O:21].[Cl:25][C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[NH:4]1[C:5]([NH:6][C:7](=[O:19])[CH2:8][O:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([CH2:16][CH2:17][NH:18][S:20]([C:29]3[CH:30]=[CH:31][C:26]([Cl:25])=[CH:27][CH:28]=3)(=[O:23])=[O:21])[CH:11]=2)=[N:1][N:2]=[N:3]1

Participants

Reactant 2

HCID 21952870Chlorobenzene sulfochloride

HCID 178510817HCID 178510817, compound

Product 1

HCID 178521404HCID 178521404, compound

Procedure

In a manner analogous to that described in Example 1, by the reaction of the appropriate 3-(2-aminoethyl)-phenoxyacetic acid (1H-tetrazol-5-yl)-amide with 4-chlorobenzene sulphochloride, there is obtained the title compound; m.p. 190°-196° C. (decomp.), after crystallisation from glacial acetic acid.

Sources & evidence

ORD record: ord-e4c4daa0639a4ca89917079f6113c4cf
Source dataset: uspto-grants-1991_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05037990

Reaction notes

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