HCID 19805562, compound → HCID 54443074, compound

HRID 2248140Notes

Reaction equation

HRID 2248140 reaction equation
[CH2:1]([O:8][C:9]([NH:11][CH2:12][CH2:13][C:14]1[CH:15]=[C:16]([O:20]C2CCCCO2)[CH:17]=[CH:18][CH:19]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)C>[CH2:1]([O:8][C:9]([NH:11][CH2:12][CH2:13][C:14]1[CH:15]=[C:16]([OH:20])[CH:17]=[CH:18][CH:19]=1)=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 19805562HCID 19805562, compound

Product 1

HCID 54443074HCID 54443074, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 16.8 g. (47.3 mMol) {3-[2-(benzyloxycarbonylamino)-ethyl]-phenyl}-tetrahydropyranyl ether, 80 ml. ethanol and 3 g. Amberlyst is stirred for 2 hours at ambient temperature, then filtered and evaporated. The last traces of ethanol are removed by blowing in air with the application of a slight vacuum at 70° C. The product is obtained in the form of a colourless oil. Yield quantitative.

Workup

  1. additionA mixture of 16.8 g
  2. filtrationfiltered
  3. customevaporated
  4. customThe last traces of ethanol are removed
  5. customby blowing in air with the application of a slight vacuum at 70° C
  6. customThe product is obtained in the form of a colourless oil
  7. customYield quantitative

Sources & evidence

ORD record
ord-254c3c7f1301401ab86ccc0ed4a1138c
Source dataset
uspto-grants-1991_08
Patent number
US05037990

Reaction notes

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