Ethyl 2-chloroethylcarbamate → ethyl N-{2-[4-(2,2,2-trifluoroethoxy)phenoxy]ethyl}carbamate

HRID 2248158Notes

Reaction equation

HRID 2248158 reaction equation
[F:1][C:2]([F:13])([F:12])[CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][CH:6]=1.Cl[CH2:15][CH2:16][NH:17][C:18](=[O:22])[O:19][CH2:20][CH3:21]>>[F:1][C:2]([F:12])([F:13])[CH2:3][O:4][C:5]1[CH:6]=[CH:7][C:8]([O:11][CH2:15][CH2:16][NH:17][C:18](=[O:22])[O:19][CH2:20][CH3:21])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 80621Ethyl 2-chloroethylcarbamateHCID 130853484-(2,2,2-Trifluoroethoxy)phenol

Product 1

HCID 14552613ethyl N-{2-[4-(2,2,2-trifluoroethoxy)phenoxy]ethyl}carbamate

Procedure

Following the procedure of Example 1, 4-(2,2,2-trifluoroethoxy)phenol (0.42 g, 2.2 mmol) and ethyl N-(2-chloroethyl)carbamate (0.40 g, 2.6 mmol) are reacted together to give ethyl N-{2-[4-(2,2,2-trifluoroethoxy)phenoxy]ethyl}carbamate (compound 28, Table A).

Workup

  1. customare reacted together

Sources & evidence

ORD record
ord-8ebc8e5a040540b8921d43eb731616b5
Source dataset
uspto-grants-1991_08
Patent number
US05037991

Reaction notes

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