Ethyl isocyanate → HCID 13939037, compound

HRID 2248188Notes

Reaction equation

HRID 2248188 reaction equation
[CH3:1][C@@H:2]([O:5][C:6]1[CH:15]=[CH:14][C:9]([O:10][CH2:11][CH2:12][OH:13])=[CH:8][CH:7]=1)[CH2:3][CH3:4].[CH2:16]([N:18]=[C:19]=[O:20])[CH3:17]>CO>[CH2:16]([NH:18][C:19](=[O:20])[O:13][CH2:12][CH2:11][O:10][C:9]1[CH:14]=[CH:15][C:6]([O:5][C@H:2]([CH3:1])[CH2:3][CH3:4])=[CH:7][CH:8]=1)[CH3:17]

Participants

4

Reactant 2

HCID 8022Ethyl isocyanateHCID 13939034HCID 13939034, compound

Product 1

HCID 13939037HCID 13939037, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Following the procedure of Example 9, the above alcohol (0.42 g, 2.0 mmol) is reacted with ethyl isocyanate (0.18 ml, 2.2 mmol) to give O-2-[(R)-4-(1-methylpropoxy)phenoxy]ethyl N-ethylcarbamate, specific rotation [α]D20 =-19.103° (c=10% in methanol).

Sources & evidence

ORD record
ord-1834cf7f7958435892b13816241175e9
Source dataset
uspto-grants-1991_08
Patent number
US05037991

Reaction notes

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