Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 5-Amino-1,3,4-trimethyl pyrazole hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Methylhydrazine | HCID 6061 | — |
| 반응물 | 2-Methyl-3-oxobutanenitrile | HCID 536905 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 5-Amino-1,3,4-trimethyl pyrazole hydrochloride | HCID 23330516 | — |
반응 단계
2-Methyl-3-keto-butyronitrile (J. Am. Chem. Soc. 79, 723, 1957) (25.25 g.) in 120 ml. ethanol was treated with 15 g. methylhydrazine while cooling. The solution was refluxed 3 hours then concentrated in vacuum, benzene added and the solution concentrated again. Ether was added to give 29.12 g. mp 70-106 of base (contained H2O). This was converted to the hydrochloride with HCl in isopropyl alcohol. HCl had mp 286°-288°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04234594 |
| 출처 데이터셋 | uspto-grants-1980_11 |
| ORD ID | ord-d0589c32ef3e44d3a284b33a207f2ca3 |
| 출처 메모 | uspto-grants-1980_11 |