3-ethyl-1-methyl-1H-pyrazol-5-amine → 1-Acetyl-2-(3-ethyl-1-methyl-5-pyrazolyl) amino-2-imidazoline

HRID 224828Notes

Reaction equation

HRID 224828 reaction equation
[NH2:1][C:2]1[N:6]([CH3:7])[N:5]=[C:4]([CH2:8][CH3:9])[CH:3]=1.[C:10]([N:13]1[CH2:17][C:16](=O)[N:15]=[CH:14]1)(=[O:12])[CH3:11]>>[C:10]([N:13]1[CH2:17][CH2:16][N:15]=[C:14]1[NH:1][C:2]1[N:6]([CH3:7])[N:5]=[C:4]([CH2:8][CH3:9])[CH:3]=1)(=[O:12])[CH3:11]

Participants

3

Reactant 2

HCID 151357823-ethyl-1-methyl-1H-pyrazol-5-amineHCID 22350258N-acetyl-2-imidazolinone

Product 1

HCID 572185821-Acetyl-2-(3-ethyl-1-methyl-5-pyrazolyl) amino-2-imidazoline

Procedure

5-Amino-3-ethyl-1-methyl pyrazole (British Pat. No. 863,060) (35.2 g.) and 1-acetyl-2-imidazolinone (43.2 g.) were reacted as described in Example I to give 1-acetyl -2-(3-ethyl-1-methyl-5-pyrazolyl) amino-2-imidazoline which was de-acetylated without purification by the method of Example II giving 39.3 g. product. mp 160°-162°

Sources & evidence

ORD record
ord-00fe1b888cf44f47bd80fbc6eb9e650c
Source dataset
uspto-grants-1980_11
Patent number
US04234594

Reaction notes

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