HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-Amino-1(3-trifluoromethylphenyl)-3-methylpyrazole hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-Amino-2-butenenitrile | HCID 70699 | — |
| Reactant | (3-(Trifluoromethyl)phenyl)hydrazine | HCID 98650 | — |
| Product | 5-Amino-1(3-trifluoromethylphenyl)-3-methylpyrazole hydrochloride | HCID 23330495 | — |
Reaction Steps
3-Trifluoromethylphenyl hydrazine (Tetrahedron, 1960, 69) (25.0 g.) was reacted with 3-amino-2-butene nitrile (12.7 g.) as described in Example XLIII to give 36.1 g. product as HCl salt, mp 222°-226°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04234594 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-dd16ca5be6944d7f8769d2b63133f47e |
| Source note | uspto-grants-1980_11 |