5-Amino-1(3-trifluoromethylphenyl)-3-methylpyrazole hydrochloride → 1-Acetyl-2[1-(3-trifluoromethylphenyl)-3-methyl-5-pyrazolyl] amino-2-imidazoline

HRID 224836Notes

Reaction equation

HRID 224836 reaction equation
Cl.[NH2:2][C:3]1[N:7]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([C:14]([F:17])([F:16])[F:15])[CH:9]=2)[N:6]=[C:5]([CH3:18])[CH:4]=1.[C:19]([N:22]1[CH2:26][CH:25]=[N:24][C:23]1=O)(=[O:21])[CH3:20]>>[C:19]([N:22]1[CH2:26][CH2:25][N:24]=[C:23]1[NH:2][C:3]1[N:7]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([C:14]([F:17])([F:16])[F:15])[CH:9]=2)[N:6]=[C:5]([CH3:18])[CH:4]=1)(=[O:21])[CH3:20]

Participants

3

Reactant 2

HCID 233304955-Amino-1(3-trifluoromethylphenyl)-3-methylpyrazole hydrochlorideHCID 699078731-Acetyl-3-imidazolinone

Product 1

HCID 572728511-Acetyl-2[1-(3-trifluoromethylphenyl)-3-methyl-5-pyrazolyl] amino-2-imidazoline

Procedure

5-Amino-1-(3-trifluoromethylphenyl)-3-methyl pyrazole HCl (20.0 g.) and 1-acetyl-3-imidazolinone (11.1 g.) were reacted as described in Example I to give 15.0 g. product. mp 173°-175°

Workup

  1. customto give 15.0 g

Sources & evidence

ORD record
ord-e4873a21561b48778cd15f46cc9e59db
Source dataset
uspto-grants-1980_11
Patent number
US04234594

Reaction notes

Loading…