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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2248467Generated: November 2, 2026

Gamma-Aminobutyric Acid → 4-Phthalimidobutyric acid

https://huagongshe.com/reaction/2248467

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGamma-Aminobutyric AcidHCID 119—
ReactantPhthalic AnhydrideHCID 6811—
SolventAcetic AcidHCID 176—
Product4-Phthalimidobutyric acidHCID 18411—

Reaction Steps

A 2 liter nitrogen flushed flask fitted with a mechanical stirrer and a reflux condenser was charged with 103 g (1 mole) of 4-aminobutyric acid (GABA), 148 g (1 mole) of phthalic anhydride and 250 ml of glacial acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05039819
Source datasetuspto-grants-1991_08
ORD IDord-eed751fa900d4d9e84a13c6ea869d7e4
Source noteuspto-grants-1991_08