Ethanol → HCID 22157539, compound

HRID 2248472Notes

Reaction equation

HRID 2248472 reaction equation
F[C:2]1[CH:3]=[N+:4]([O-])[CH:5]=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9].[N:12]1([NH2:21])[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13]1.C([OH:24])C>>[N+:8]([C:7]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[NH+:21]([O-:24])[N:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13]1)([O-:10])=[O:9]

Participants

4

Reactant 3

HCID 702EthanolHCID 5940283-Fluoro-4-nitropyridin-1-ium-1-olateHCID 6432211-Aminoindole

Product 1

HCID 22157539HCID 22157539, compound

Procedure

A solution of 3-fluoro-4-nitro-pyridine-N-oxide (5 g) and 1H-indol-1-amine (4.2 g) in 25 ml of ethanol was stirred four hours at reflux. The solution was cooled and the product collected and dried to give 4 g of solid, d 195°. This material was recrystallized from ethanol/ether to give 2.2 g of solid, d 200°-201°.

Workup

  1. temperatureat reflux
  2. temperatureThe solution was cooled
  3. customthe product collected
  4. customdried

Sources & evidence

ORD record
ord-e542daf89047411d8d54fcaa81b378f4
Source dataset
uspto-grants-1991_08
Patent number
US05039811

Reaction notes

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