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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2248477Generated: October 30, 2026

4-Chloropyridine hydrochloride → (2-Methyl-indol-1-yl)-pyridin-4-yl-amine

https://huagongshe.com/reaction/2248477

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloropyridine hydrochlorideHCID 81852—
Reactant2-Methyl-1H-indol-1-amineHCID 12427291—
Product(2-Methyl-indol-1-yl)-pyridin-4-yl-amineHCID 10799122—

Reaction Steps

The title compound was prepared from 2-methyl-1H-indol-1-amine and 4-chloropyridine hydrochloride at 120° C. for 30 minutes in substantially the same manner as in Example 1, m.p. 75°-78° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05039811
Source datasetuspto-grants-1991_08
ORD IDord-8290763803c94dbdbb2ad8ad139937d8
Source noteuspto-grants-1991_08