N-acetyl-2-imidazolinone → HCID 12763806, compound

HRID 224848Notes

Reaction equation

HRID 224848 reaction equation
Cl.[NH2:2][C:3]1[N:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[CH3:14])[N:6]=[C:5]([CH3:15])[CH:4]=1.[C:16]([N:19]1[CH2:23][C:22](=O)[N:21]=[CH:20]1)(=[O:18])[CH3:17]>>[C:16]([N:19]1[CH2:23][CH2:22][N:21]=[C:20]1[NH:2][C:3]1[N:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[CH3:14])[N:6]=[C:5]([CH3:15])[CH:4]=1)(=[O:18])[CH3:17]

Participants

3

Reactant 2

HCID 22350258N-acetyl-2-imidazolinoneHCID 44891494HCID 44891494, compound

Product 1

HCID 12763806HCID 12763806, compound

Procedure

5-Amino-3-methyl-1-(2-methylphenyl)pyrazole HCl (Farmaco, 19, 638, 1964) (26.5 g.) and 1-acetyl-2-imidazolinone (18.2 g.) were reacted as described in Example I to give 12.6 g. product, mp 160°-161°.

Workup

  1. customto give 12.6 g

Sources & evidence

ORD record
ord-4bf3ffb0bf6e49e6aaf67dce47028bd5
Source dataset
uspto-grants-1980_11
Patent number
US04234594

Reaction notes

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