HCID 178491600, compound → HCID 178491599, compound

Participants

Reaction Steps

390 mg of N-[3-[[N2 -(benzyloxycarbonyl)-N5 -(N-nitroamidino)-L-ornithyl]amino]-p-anisoyl]-β-alanine benzyl ester and 160 mg of Pd/C (5%) are stirred in 8 ml of formic acid for 5 hours under hydrogen. The filtered solution is evaporated and the residue is purified on silica gel with methanol-formic acid (99:1). There are obtained 195 mg of N-[3-(L-arginylamino)-p-anisoyl]-β-alanine formate (1:2), [α]D20 =+46.6° (H2O, c=0.5%).

Provenance & Evidence