Ethanol → HCID 67827891, compound

Participants

Reaction Steps

500 mg of N-[m-[[N5 -(benzyloxycarbonyl)-N2 -t-butoxycarbonyl-L-ornithyl]amino]benzoyl]-β-alanine benzyl ester, 10 ml of ethanol, 0.05 ml of acetic acid and 125 mg of Pd/C are stirred under hydrogen for 3.5 hours. The reaction mixture is filtered and the filtrate is evaporated in a vacuum. There are obtained 333 mg of N-[m-[[(S)-N2 -(t-butoxycarbonyl)-L-ornithyl]amino]benzoyl]-β-alanine acetate (1:1), [α]D =-18.1° (MeOH, c=0.44%).

Provenance & Evidence