HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-4-chlorobenzoic acid → 3-[5-(1-t-Butoxyformamido)valeramido]-4-chlorobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-4-chlorobenzoic acid | HCID 76092 | — |
| Reactant | 5-(((Tert-butoxy)carbonyl)amino)pentanoic acid | HCID 545848 | — |
| Product | 3-[5-(1-t-Butoxyformamido)valeramido]-4-chlorobenzoic acid | HCID 53751622 | — |
Reaction Steps
For the preparation of the starting material, 5-[1-(t-butoxy)formamido]valeric acid and 3-amino-4-chlorobenzoic acid are coupled to give 3-[5-(1-t-butoxyformamido)valeramido]-4-chlorobenzoic acid, m.p. 203° C., and the latter is coupled with β-alanine t-butyl ester to give N-[3-[5-(1-t-butoxyformamido)valeramido]-4-chlorobenzoyl]-β-alanine t-butyl ester, MS: 498 (60, M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05039805 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-64055d80423c4760b5e2dd3b8fc9038a |
| Source note | uspto-grants-1991_08 |