HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylanthranilic acid → 3-[5-(1-t-Butoxyformamido)valeramido]-p-toluic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylanthranilic acid | HCID 75316 | — |
| Reactant | 5-(((Tert-butoxy)carbonyl)amino)pentanoic acid | HCID 545848 | — |
| Product | 3-[5-(1-t-Butoxyformamido)valeramido]-p-toluic acid | HCID 57076650 | — |
Reaction Steps
For the preparation of the starting material, 5-[1-(t-butoxy)formamido]valeric acid and 3-amino-p-toluic acid are coupled to give 3-[5-(1-t-butoxyformamido)valeramido]-p-toluic acid, m.p. 212° C., and the latter is coupled with β-alanine benzyl ester to give N-[3-[5-(1-t-butoxyformamido)valeramido]-p-toluoyl]-β-alanine benzyl ester, m.p. 112°-113° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05039805 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-9fccd688e62741b1b3aa8afa5bb992ad |
| Source note | uspto-grants-1991_08 |