5-Aminosalicylic Acid → HCID 53824169, compound

HRID 2248513Notes

Reaction equation

HRID 2248513 reaction equation
[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[NH2:16][C:17]1[CH:25]=[C:21]([C:22]([OH:24])=[O:23])[C:20]([OH:26])=[CH:19][CH:18]=1>>[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([NH:16][C:17]1[CH:25]=[C:21]([C:22]([OH:24])=[O:23])[C:20]([OH:26])=[CH:19][CH:18]=1)=[O:15])=[O:7])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 40755-Aminosalicylic AcidHCID 5458485-(((Tert-butoxy)carbonyl)amino)pentanoic acid

Product 1

HCID 53824169HCID 53824169, compound

Procedure

5-[1-(t-Butoxy)formamido]valeric acid is coupled with 5-aminosalicyclic acid to give 5-[5-(1-t-butoxyformamido)valeramido]salicylic acid, m.p. 181° C.

Sources & evidence

ORD record
ord-b1a4c54e395f4954a39ac305ef52474e
Source dataset
uspto-grants-1991_08
Patent number
US05039805

Reaction notes

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